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br Materials and methods br Results
2020-08-04
Materials and methods Results Discussion Because everolimus alleviates CMV infection in transplant recipients, we first tried to characterise the anti-CMV action without pretreatment, as other researchers have done (Kudchodkar et al., 2004, 2007; Moorman and Shenk, 2010). Although CMV repli
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br Materials and methods br Results br Discussion Consistent
2020-08-03
Materials and methods Results Discussion Consistent with previous reports (Barr et al., 2010, Vuong et al., 2010), the current study demonstrates that rats treated with amphetamine exhibit heightened anxiety states during withdrawal. Furthermore, icv. infusion of a CRF2 receptor antagonist
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IPT b s low expression level in dwarfing
2020-08-03
IPT5b\'s low expression level in dwarfing rootstocks suggests its key role in regulating cytokinin biosynthesis (Fig. 1b). The known IPT proteins that are highly homologous to apple IPT5b were found in plants by homologous alignment (Fig. 2a), and further analysis indicated a common structural char
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A structural model for the
2020-08-03
A structural model for the unprecedented interactions between UBE2S, its target (i.e., a Ub that has been linked already to an APC/C substrate), and APC/C was generated by hybrid structural studies merging information from NMR, crosslinking, and mutational data with a low-resolution cryo-EM map of A
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br Experimental br Results and discussion br Conclusions
2020-08-03
Experimental Results and discussion Conclusions Acknowledgements The work was financially supported by the Natural Science Foundation of Liaoning Province of China (Grant No. 201602693). Introduction Hormone therapy (HT) is the treatment of choice for the management of bothersome men
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The GH family includes also xylanases
2020-08-03
The GH30 family includes also xylanases which are not MeGlcA-dependent. Most of them are grouped to GH30_7 subfamily that includes XynIV from Trichoderma reesei showing exo- and endo-xylanase activity [11] and XYLD from Bispora sp. MEY-1 [12] having activity towards glucuronoxylan and arabinoxylan,
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In order to produce non diffusible
2020-08-03
In order to produce non-diffusible chelates that might be suited for use in solid (agar) media, the series of 6,7-dibromo-2,3-dihydroxynaphthalene substrates 18b, 20b, 24b and 26b were prepared (Table 3) with the expectation that the incorporation of the bromine substituents would reduce the solubil
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In summary our data unveil a previously unknown function
2020-08-03
In summary, our data unveil a previously unknown function for CIITA in vascular endothelial cells. Small-molecule inhibitors of SUV39H1 have been discovered or developed although their specificities are questionable [56]. Screening for compounds that selectively inhibit SUV39H1 activity may yield no
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br Results br Discussion br
2020-08-03
Results Discussion Materials and Methods Acknowledgments Mélanie Lemor thanks the French Institute for the Exploitation of the Sea (Ifremer) and the Regional Council of Brittany for funding. The dNTP/rNTP measurements were performed in the laboratory of Dr. Chabes, Umeå University. This
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br Regulation of DGK activity Activation of
2020-08-03
Regulation of DGK activity Activation of the DGKs is complex and unique for each DGK isotype. In most cases, DGKs must translocate to a membrane compartment to access DAG. However, translocation does not necessarily activate the enzyme [57]. In addition, DGK activity can be modified by other cofa
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Carteolol HCl receptor As the IC substitution pattern trimet
2020-08-01
As the IC261 substitution pattern (2,4,6-trimethoxybenzene) was found to be important for the activity, it was systematically varied into 2,3,4- and 3,4,5-trimethoxybenzene (, ). These two derivatives also exert a significant Carteolol HCl receptor in total Aβ. Although the o-positions of (Aβ=54%,
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To guarantee that there is at least one
2020-07-31
To guarantee that there is at least one solution to the NBLP problem, we assume that the constrained region S is nonempty and compact. At the same time, for some fixed x∈X, we assume that the lower level problem is a convex optimization problem satisfying the Mangasarian–Fromovitz constraints qualif
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After exposure to P lima expression level of CYP
2020-07-31
After exposure to P. lima, Zinc protoporphyrin IX level of CYP3A4 and CYP2D14-like was found to be altered in gill and digestive gland, whereas OA content was found to be increased in gill and digestive gland which was in accordance with the previous report (Bauder et al., 2001; Rossignoli and Blanc
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In the alternative scenario collagen binding
2020-07-31
In the alternative scenario, collagen binding to two independent sites would trigger the transition from the inactive to the active DDR dimer, conceivably by amplifying the small changes in the collagen-binding loops of the DS domain (Figure 3). This situation would be more akin to the EGF-EGF recep
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gtpase br Experimental Procedures br Author Contributions br
2020-07-31
Experimental Procedures Author Contributions Acknowledgments Introduction Oxysterols came to prominence in the late 1970\'s with the oxysterol hypothesis which proposed that the suppressive effect of cholesterol on its own synthesis is mediated through oxysterols not by cholesterol itsel
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